Yesterday, AYA NEO, AMD 4500U-based handheld gaming PC, launched its Indiegogo crowdfunding campaign. While their ambitious device might be the first AMD-based handheld gaming PC, they won't be the last. As reported by @geargeeksp on YouTube, GPD is also working on an AMD-based handheld gaming PC. According to their international marketing manager, YYang, their preliminary model is based on the 5800U processor and have it running Devil May Cry 5.
Everything is still at an early stage and the device's look has yet to be seen but GPD will indeed work on an AMD-based device. Apparently, it could be a new MAX model, rather than the GPD Win 4; meaning that it will feature a clamshell design. As for what a 5800U-based handheld means for PC games and emulators, you can watch @geargeeksp 's video that elaborates on the possibilities:
https://gbatemp.net/threads/gpd-is-reportedly-working-on-an-amd-5800u-based-handheld-pc.584357/
